# Issue with MiXCR Clonotyping Output and Clonotype Browser Dataset Selection

**URL:** <https://community.platforma.bio/t/issue-with-mixcr-clonotyping-output-and-clonotype-browser-dataset-selection/60>\
**Category:** Ask a question\
**Tags:** platforma, mixcr\
**Created:** [May 7, 2025, 9:44am UTC](https://community.platforma.bio/t/issue-with-mixcr-clonotyping-output-and-clonotype-browser-dataset-selection/60 "2025-05-07T09:44:04Z")\
**Posts on this page:** 5\
**Page:** 1

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**Author:** ![gonzalolazaro](https://avatars.discourse-cdn.com/v4/letter/g/85f322/32.png) [@gonzalolazaro](https://community.platforma.bio/u/gonzalolazaro)\
**Post date:** [May 7, 2025, 9:44am UTC](https://community.platforma.bio/t/issue-with-mixcr-clonotyping-output-and-clonotype-browser-dataset-selection/60/1 "2025-05-07T09:44:04Z")

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Hi,

I’m working with Platforma to analyze TCR beta sequencing libraries generated using the SMARTer TCR a/b Profiling Kit v2 (with UMIs). I’m currently processing three different sets of samples.  
After running the “MiXCR Clonotyping” block, I receive the message:  
“Some outputs have errors”, as shown below:

 ![screenshot](https://canada1.discourse-cdn.com/flex012/uploads/platforma/original/1X/3123bbc26e5d774ff2e6dac77d5b0c5506171297.png)

Despite this, I see that each sample has an output report that states the analysis was completed successfully. However, when I try to proceed to the “Clonotype Browser” step (to annotate, track, and filter clonotypes), no dataset appears under “Samples & Data”, so I’m unable to continue the analysis.

I suspect the issue originates from one or more samples producing partial or malformed results during MiXCR Clonotyping, potentially preventing the creation of a complete dataset.

Here are a few specific questions I have:

- How can I identify which sample(s) are causing the error in MiXCR Clonotyping? Are there logs or specific indicators I can check?
- Is it possible that one problematic sample is blocking the creation of the dataset required for Clonotype Browser? (e.g., an unexpected number of input files or metadata issues)
- Could this issue be caused by an outdated version of Platforma or any of its dependencies (e.g., Python, MiXCR version, workflow components)?
- Finally, does the presence of UMIs require special configuration that might affect dataset compatibility?

Any suggestions or troubleshooting steps would be greatly appreciated.

Thanks in advance!

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**Author:** ![ssm123](https://avatars.discourse-cdn.com/v4/letter/s/ec9cab/32.png) [@ssm123](https://community.platforma.bio/u/ssm123)\
**Post date:** [September 13, 2025, 3:34am UTC](https://community.platforma.bio/t/issue-with-mixcr-clonotyping-output-and-clonotype-browser-dataset-selection/60/2 "2025-09-13T03:34:23Z")

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I am having a similar issue with Takara Smart-Seq

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**Author:** ![PoslavskySV](https://yyz2.discourse-cdn.com/flex012/user_avatar/community.platforma.bio/poslavskysv/32/27_2.png) [@PoslavskySV](https://community.platforma.bio/u/PoslavskySV)\
**Post date:** [September 13, 2025, 1:33pm UTC](https://community.platforma.bio/t/issue-with-mixcr-clonotyping-output-and-clonotype-browser-dataset-selection/60/3 "2025-09-13T13:33:40Z")

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Hi guys, thank you for reporting. Could you please attach a full error message (there is a copy button top right)? Another questions:

- are you running backend in “built-in” mode or connect to a server ?
- which OS you use (Windows/Mac/Linux) ?

Thank you !

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**Author:** ![ssm123](https://avatars.discourse-cdn.com/v4/letter/s/ec9cab/32.png) [@ssm123](https://community.platforma.bio/u/ssm123)\
**Post date:** [September 13, 2025, 10:05pm UTC](https://community.platforma.bio/t/issue-with-mixcr-clonotyping-output-and-clonotype-browser-dataset-selection/60/4 "2025-09-13T22:05:42Z")

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I am actually able to see 1 TCR b clonotype from 1 sample (although this sample should have 92 clonotypes) and the dataset in total should have \>500 TCR clonotypes based on the MIXCR clonotyping which was run successfully. I was actually able to clear the error below (by installing the 7zip folder in the proper location) and restarted software twice but I still do not see more clonotypes loading in the browser.

PlQuickJSError: PlErrorReport: PlRunnerError:  
command: /Users/mm/Platforma/local/packages/installed/platforma-open/software/platforma-open/milaboratories.software-binary-collection.software-7zip/main/1.2.0-macosx-x64.0x5B10C/bin/7zz  
exit code: 127  
working directory: workdirs/0x823EF  
stdout:  
env: /Users/mm/Platforma/local/packages/installed/platforma-open/software/platforma-open/milaboratories.software-binary-collection.software-7zip/main/1.2.0-macosx-x64.0x5B10C/bin/7zz: No such file or directory

I am using MacOS and in built in mode.

If you provide an email I can send screeshots of my MIXCR clonotyping output and clonotype browser output.

Thank you!

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**Author:** ![PoslavskySV](https://yyz2.discourse-cdn.com/flex012/user_avatar/community.platforma.bio/poslavskysv/32/27_2.png) [@PoslavskySV](https://community.platforma.bio/u/PoslavskySV)\
**Post date:** [September 13, 2025, 11:33pm UTC](https://community.platforma.bio/t/issue-with-mixcr-clonotyping-output-and-clonotype-browser-dataset-selection/60/5 "2025-09-13T23:33:56Z")

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Thanks for prompt reply! Could you please share screenshots to [support@milaboratories.com](mailto:support@milaboratories.com) ? Also, are you running the most recent version of the app?
